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00:02 | Mhm. All right guys. Good . I hope everyone is sent me |
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00:11 | . I am I'm not I'm barely . I'm just skating in on my |
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00:19 | in the morning. So, what we're gonna do is we're gonna |
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00:22 | looking at again. We're gonna kind take the approach like we did on |
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00:26 | last week. We're gonna die first the peripheral nervous system. We're going |
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00:29 | deal with cranial nerves and then we're move back to the central nervous system |
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00:33 | we're going to finish up with the of the central nervous system. And |
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00:37 | reason we kind of do this is uh when we talk about cranial nerves |
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00:40 | associated with the cerebral the brain So we want to use that kind |
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00:45 | as a springboard to jump back in opposed to going here, spinal |
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00:49 | Here's cranial nerves and then just kind leaving him alone. All right, |
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00:53 | , that's our starting point today is be the cranial nerves. A lot |
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00:55 | people freak out about them. See that trigger warning again. I told |
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00:59 | I wouldn't do. But here I . Um You shouldn't. Alright. |
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01:04 | really shouldn't. I heard here the going on. How do we deal |
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01:07 | cranial nerves? Look at the the name tells you what it |
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01:10 | All right. That's that's what it down to Now, look this is |
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01:14 | is why they're named or number the they're numbered. All right, That's |
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01:18 | this picture is showing you. You see here if you take the cerebral |
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01:21 | laid back and look at the base then you're coming down through the other |
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01:26 | of the brain. And then down would be the uh well this is |
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01:29 | brain stem. This would be where spinal cord you can see it goes |
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01:34 | , so on and so on all way down. Okay. That's how |
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01:38 | got their numbering. Because you scientists are really, really, really |
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01:43 | people and we just look at the and we just kind of just label |
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01:47 | as we go along now with regard cranial nerves versus spinal nerves. How |
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01:53 | they different? What's what's the difference well, spinal nerves dealt with innovation |
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01:58 | everything from here on down, We talked about the arms, we |
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02:02 | about the trunk. We talked about legs. And so that's what the |
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02:06 | nerves are for. So, the nerves are for that what the cranial |
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02:09 | for everything above that. So, basically the head and neck region. |
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02:14 | , so it kind of keeps it , really simple for us. All |
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02:17 | . And like I said, they're named based on their function. |
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02:20 | if you ever like, I don't what this is. I mean, |
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02:23 | of the time, the reason that get lost with this is they just |
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02:26 | on the number. Right? And really kind of have to attach that |
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02:31 | with the name. All right. with regard to their function, |
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02:35 | hearing, taste, smell, touch the face or sensation of the |
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02:39 | scalp, eye movement, chewing, . You see what I'm getting at |
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02:42 | . Everything that's here. On All right. Now, there's one |
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02:47 | sticks out as being different from all others. And this goes back to |
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02:50 | Sesame Street learning. You remember Sesame ? Did you all stay home and |
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02:55 | Sesame Street one time in your Yeah. See you're starting to become |
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03:00 | generation where they didn't go to public . You have cable your entire |
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03:06 | right? When I when I was , So you had PBS kids, |
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03:11 | ? So that's that's how you guys of it when I was young. |
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03:14 | was just you didn't have cable, ? Or if you did have |
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03:18 | there was nothing worth watching on it the day because it was all geared |
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03:22 | adults. So, Sesame Street was we did when we were sick, |
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03:25 | at home. You watch Sesame And there's something we all learned on |
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03:29 | Street. one of these things is like the others. You can see |
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03:35 | of a sudden I just triggered you . One of these things is kind |
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03:38 | the same, right? You don't that? No, you didn't watch |
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03:44 | . And this is why education has through the floor because we didn't watch |
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03:50 | Street, right, Snuffleupagus. Come . I mean a grand hallucination. |
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03:58 | big bird has. I mean All . Anyway, so one of these |
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04:04 | stands out as being different from all others. And so we'll point that |
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04:08 | out. That's the easy one to . And then all the other ones |
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04:11 | of look at the names. what we're gonna do, we're just |
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04:13 | walk through them. All. All . The starting one is the olfactory |
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04:17 | , plural. We usually sell factory , which is just easy. And |
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04:22 | this structure right? Here, you see it coming out. There is |
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04:25 | old factory track note. That's not not the olfactory bulb. It's these |
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04:29 | that look like the bristles on a . There's lots of nerves. And |
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04:32 | we get into the olfactory system, going to see this more clearly. |
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04:36 | basically it's a series of nerves that from the olfactory bulb. So, |
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04:40 | you're looking at it, you'd be at it this way. All these |
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04:43 | coming out at you, what we're is we're looking at on the |
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04:45 | And so we're looking at the bristles down. Alright, this plays a |
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04:50 | in olfaction. Alright. That's your of smell. The optic nerve is |
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04:55 | second one. You can see there's there's two there criss crossing at the |
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05:00 | eye asthma. All right. They a role in vision so far, |
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05:03 | good. These are really easy. right. Third one is the ocular |
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05:07 | nerve. Ocular motor says write the . Ocular motor is the eye |
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05:11 | All right. So what it It primarily innovates the extrinsic eye |
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05:16 | Alright, when you hear the word versus the word intrinsic. Extrinsic means |
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05:20 | of intrinsic means internal too. So, when you hear outside eye |
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05:27 | , these are the muscles that are to the outside of the eye that |
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05:30 | it to move back and forth, you to do the shifty eyes like |
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05:35 | . Okay. And up and Alright. There's some autonomic innovation as |
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05:40 | . So, they play a role innovating the future possibilities. All |
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05:43 | Well, let's stink your pupil. It's the muscle, the smooth muscle |
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05:47 | your eye that contracts so that when really, really bright, you don't |
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05:52 | yourself. All right. The opposite would be the dilator. Alright. |
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05:58 | also have the truck. Clear I don't know where the name comes |
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06:01 | , honestly, I've never bothered looking . Don't ever ask me. All |
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06:06 | . It innovates one extrinsic eye All right. Here's how you can |
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06:10 | it. Remember that one time you to cheat on a test just at |
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06:16 | time. Right. And what did do? You look down at your |
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06:20 | paper without moving your head. You down right over there. That's what |
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06:24 | clear. Does. All right. eye muscle is the superior oblique. |
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06:28 | allows you to look. It's the . I there were like the the |
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06:31 | muscle. Alright. Honestly. How really say? It really is up |
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06:38 | you. But this this is kind how you help yourself to make those |
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06:41 | . So, the truck clear Is one in trick extrinsic eye muscles. |
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06:48 | trigeminal even here Gemini the twins. now. I'm not having you try |
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06:58 | would be the triplets. All And that's what the trigeminal nerve |
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07:02 | There's three branches. So here you see the big old honkin nerve and |
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07:06 | goes 123 branches. All right. innovates muscles in the face or not |
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07:12 | . It innovates the sensory nerves. where the sensory nerves come from. |
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07:17 | , the sensations on your faces through tri jim. Also the muscles for |
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07:20 | our through the try jim. The is another one of those weird extrinsic |
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07:26 | muscles. All right. So, one nerve or 11 muscle in the |
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07:32 | and it's called the abductor. So it's the abductions muscle. All |
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07:36 | . So, that's what it It abducts and turns it I out |
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07:40 | . My daughter was born on one without this nerve. And so when |
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07:46 | have her look one way she can just fine, but you look the |
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07:48 | way the other. I just kind right to there and everyone goes away |
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07:51 | there. It's really weird. Okay. So that's the abdu |
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07:58 | So, it's the abductor. That's you can think about it abducts facial |
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08:03 | . What do you think that innovates . There you go. So, |
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08:07 | the facial muscles, or the muscles expression is how you can think |
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08:11 | It also interacts celebrating glands and the gland. The lack from a gland |
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08:16 | the eye. Economic. And then also innovates the tongue so that you |
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08:21 | get the sensation of taste. That's anterior two thirds. When you hear |
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08:26 | two thirds. That's the part of tongue that you can see. All |
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08:29 | . There's a posterior third of the you can't see. All right. |
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08:33 | , even if he grabs one go, the tongue extends back in |
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08:38 | . So, that's the posterior What you can't see. Alright, |
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08:42 | , now we're getting to the fun . All right. The stimulus. |
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08:47 | . All right. The vestibular apparatus a structure in the ear. |
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08:52 | That's responsible for equilibrium, imbalance in body. All right. So, |
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08:57 | half of it. And the coke is the other structure in that |
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09:02 | Or in that in the bone, , it's responsible for hearing. And |
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09:06 | we get to that in the next , I'll be able to point those |
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09:09 | . So, that's where the name from. So, these are the |
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09:12 | of the inner ear. This There is the cochlear that right? |
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09:16 | is the vestibular apparatus. And that's nerve the stimulus. Cochlear nerve. |
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09:22 | where the name comes from. Moving to number nine glossy referential glossary to |
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09:29 | to the tongue. The Pharynx is fancy word for your throat. |
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09:33 | this is the tongue and throat All right. So, what are |
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09:38 | looking at? Sensory input and muscles the pharynx as well as taste on |
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09:46 | tongue. So, this is salivary . A glass of orange juice. |
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09:54 | I'm going really faster. These that's all I can tell you what |
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09:59 | name me. Right. It's a more fun when you have a brain |
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10:04 | you can sit there and play with , wow. All right. Vagus |
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10:11 | . This is the one thing that's like the others. All right. |
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10:14 | confuse it with the vagus nerve, I was going to try to come |
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10:18 | some dad joke there just wasn't gonna . Alright. The vagus nerve is |
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10:24 | nerve that innovates all the viscera of body. That's where all this is |
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10:29 | to show you. Okay. It with the pharynx and it works its |
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10:33 | down. So it goes through heart, digestive system. Everything that |
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10:38 | your viscera is innovated via the vagus . All right. So, the |
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10:46 | Parsons, pharynx and larynx. Everything is autonomic. The accessory nerve is |
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10:56 | for women to remember than men, you call earrings and necklaces ladies. |
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11:01 | accessories. All right, guys, we have accessories? Mhm. That's |
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11:09 | an accessory. That's a watch. a timepiece. We don't. We |
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11:14 | have accessories. All right. But easy way to remember is your girlfriend |
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11:18 | your wife or your sister or your likes to receive accessories on valentine's |
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11:25 | I don't know whatever the idea muscles of the neck, specifically the |
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11:30 | and sternal colloidal maths toyed. So trapezius you're probably familiar with just a |
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11:35 | Clyde. Um asteroid is found in . And what allows you to do |
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11:39 | ? All right. The last one the hyper glass owner of hippo means |
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11:43 | glass, as I said, is . And so these are muscles that |
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11:49 | the tongue. So these are both and extrinsic meaning. It allows you |
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11:53 | do things like this. Can everyone that? This is the fun part |
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11:59 | ruling. Yeah, the taco tongue what I call it. There's a |
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12:04 | actual name for it. No, cannot do the three. All |
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12:09 | There's some of you who can do three. I cannot do the |
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12:12 | My son can't do just the taco . He gets really upset. How |
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12:15 | you do that? You're born that . And it also allows to do |
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12:21 | like this. I know, So hipaa classic muscles of the |
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12:28 | Easy. Yeah. So you just the name and the number two what |
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12:33 | does. And again, most of tell you what they do. So |
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12:39 | you look at it don't panic and I said, one of them is |
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12:42 | weird one, Vegas. That's the one I guess Vegas and all |
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12:49 | So what we're gonna do now is gonna move back into the central nervous |
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12:52 | . So those were peripheral system. ? Because their nerves nerves is always |
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12:57 | nervous system. And so what we're do is we're gonna now just kind |
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13:00 | jump through, we're gonna do the really quick and then we're gonna go |
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13:04 | the to the dying cephalon and then gonna do the cerebral. So, |
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13:09 | we kind of worked our way up the brain stem into the brain |
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13:15 | rather than working our way down, is normally what you do. All |
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13:19 | . So, when you look at picture, what I want you to |
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13:22 | . So, here is the cerebral what they've done over here is they've |
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13:25 | the structure and they spread it out that you can kind of see where |
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13:28 | different areas are. And they've color it for you. All right. |
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13:33 | , I like to think of the , which is what this structure is |
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13:37 | kind of like. And again, is a very, very niche. |
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13:41 | kind of like the Gpu and a . All right. And so you |
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13:45 | let me go, okay, he's their talk now. And yeah, |
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13:48 | basically back when they were doing they realize, you know, there's |
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13:53 | in terms of the amount of speed doing graphics and stuff on the |
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13:57 | So, someone got the brilliant idea say, hey, you know why |
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13:59 | created our own special chip and put to the side and then we'll do |
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14:04 | the graphics processing over here and will the computer to do all their other |
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14:09 | on the main chip. And like brilliant. And then now people are |
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14:14 | crypto with it. Okay. I a great leap there again. All |
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14:20 | . So that's kind of the same as the brain has this little structure |
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14:23 | does processing on the side. That's whole cerebellum, literally cerebellum means little |
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14:32 | . So again, there's that you know, say hello to my |
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14:35 | brain. You think Brandon? I'm it? Yeah. All right. |
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14:48 | it's connected to the brain stem via ponds. There's three different bad |
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14:53 | We've already talked about them. One kind of on the medulla, one |
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14:56 | on the pond, One is kind divided between the ponds and the |
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14:59 | So I have up here some So basically that's that's how it's uh |
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15:04 | way off to the side. And what's happening is you have tracks |
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15:07 | are coming in and the tracks that leaving so that it can do this |
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15:12 | on the side. Now, structurally can see that there is a cortex |
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15:16 | you again, when you hear the cortex, that means a layer that's |
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15:19 | on the outside. This cortex is matter, which means that's where the |
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15:24 | bodies are located. It also has white matter, which means these are |
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15:29 | of axons that are traveling away from area. So, gray matter and |
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15:33 | matter are located there. The name the gray matter is referred to |
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15:40 | All right. The white matters referred is a white matter you can see |
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15:44 | referred to as the arbor vitae. right. Now, for those you |
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15:49 | your latin. What is arbor Tree of life? What is folio |
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15:58 | ? Yes, here, this helps , foliage foliage. All right. |
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16:04 | here have a portfolio. Alright, is a portable group of pages which |
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16:12 | referred to as leaves or sheaves You get your all your latin in |
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16:17 | little go. These are like the latin words. I know. |
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16:22 | so you can see that the branches the white matter go up into the |
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16:28 | uh regions. And so that's why get these folio. All right. |
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16:33 | , there are three sections alright? a flock, yellow nodule, |
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16:37 | We have the central Vermont which I to pull out and we have these |
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16:41 | hemispheres which I want to point All right, The follicular, modular |
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16:46 | plays a major role in balancing eye . Okay, so the idea is |
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16:55 | I'm gonna give you a dumb Okay, every watch your pigeon, |
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17:00 | does its head do? Right. so, as part of its movement |
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17:05 | like that. Well, your movement your balance is also based on how |
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17:11 | eyes are doing. If you've watched who like you spin the chair real |
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17:16 | , their eyes are still doing this watch. They're trying to manage the |
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17:20 | or the perception of the world with body and that's what we're talking about |
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17:25 | . Okay. The central verma's plays role in posture, locomotion, motor |
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17:31 | and basically helps you produce nice smooth . Are coordinated movements. I hope |
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17:38 | starting to see a theme here. , finally, the lateral hemispheres, |
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17:42 | , it's in uh in contact it's not gonna be up here, |
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17:46 | frontal lobe. So that's gonna be cerebral, basically planning, practicing and |
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17:51 | complex movements. What is the cerebellum a role in then movement. Does |
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17:56 | actually cause movement? What do you ? Does any of that say innovates |
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18:03 | ? No. So what it's all right. Said it's a processor |
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18:08 | sits off to the side we're going see here in the cerebral cerebral um |
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18:13 | primarily responsible for movement. All It's probably the frontal lobe is |
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18:19 | oh, I need to move. the part that's innovating the muscle. |
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18:23 | so what happens is you make a , right? My plan is to |
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18:28 | one step forward. So all processing me to be able to do that |
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18:33 | got sent to the cerebellum and hey, I've got this plan, |
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18:36 | want to move forward like a Um Is this an okay plan? |
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18:39 | the cerebellum sits there and processes it goes okay based on what we where |
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18:44 | are, what we're doing, how standing where our weight is located, |
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18:48 | yada. This is what you need do. And it does this in |
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18:51 | time. As you're moving help. put perspective on this and I'll answer |
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18:56 | question. Have you ever been walking one of the really, really smooth |
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19:01 | in Houston while checking your phone and hit one of those really smooth |
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19:08 | You know what I'm talking about, ? You haven't lived in Houston long |
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19:12 | to know that there's no such thing a sidewalk. Yeah, I felt |
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19:16 | I played the sarcastic card there. are the sidewalks in Houston, |
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19:22 | You're walking along doing your phone thing I've watched you all foot hits that |
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19:32 | . What do you do? Dr trip writes like this. Mhm. |
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19:44 | ? Right? The reason you're able catch yourself as your cerebellum said this |
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19:49 | the plan. The plan has been . We've got to re calculate what |
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19:54 | plan is and it does. So real time, which is why you |
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19:57 | follow your face most of the time your phone, which would even be |
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20:04 | . It's doing all that. All . Here's a time out. Do |
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20:08 | write this down. Okay? As said, this is a processor that's |
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20:13 | put off to the side. There's group in Arkansas that called themselves? |
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20:17 | MRI group. All right. And they do is they like to go |
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20:21 | in MRI machines and do stuff they this at night at the hospital |
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20:25 | researchers. Okay. And the best of research is doing stuff on |
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20:31 | I mean, no, it's finding people who are that's where they put |
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20:35 | in the MRI machine. They like a piano, read a book, |
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20:38 | this. And you just want to what the brain does while while it's |
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20:40 | on rather than always working on Right. And so, what they |
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20:46 | and this hasn't been confirmed. This why we're just mentioning it is that |
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20:51 | looks like the cerebellum also plans other beyond movement. Like as you're thinking |
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20:58 | daydreaming it's sitting there processing information and , well, this might be a |
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21:02 | idea. Why don't you try doing doing that? So, It may |
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21:06 | in about 10 years in the You can see it's not just all |
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21:09 | movement, but for today it's That's a planning processing movement. |
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21:16 | ma'am. Still going to see Mhm. Yes. Mr objective. |
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21:26 | . So, she's asking how does all work in a nutshell? |
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21:29 | How does the serene room and the talk to each other? Right. |
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21:34 | answer is I don't want to talk . Yeah. All right. And |
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21:37 | reason for that. All right. , I told you at the beginning |
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21:40 | the what we like to do as . We like to throw things in |
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21:43 | baskets. Right. And so it's this is what the street room does |
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21:46 | what the cerebellum does is what the cephalon does, and that's the simple |
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21:50 | that we're playing with right now. we're gonna do is we're gonna come |
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21:52 | in the next unit, we're going talk about movement. So we're going |
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21:55 | create a different basket and say this the movement basket. And then what |
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21:58 | gonna do is going to hear is three run the cerebellum hypothalamus. The |
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22:01 | do clay and all these play a in how your movement occurs. And |
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22:04 | is how it works. And if tell that to you now, you're |
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22:07 | throw things at me and I don't to do that yet. Yeah, |
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22:13 | right. I'll be like, I'm . All right. So the cerebellum |
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22:20 | , the dying cephalon, alright, word for saying a bunch of |
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22:25 | You can see what all the structures in common. They're all part or |
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22:29 | the thalamus. Alright, so the is kind of like the central hub |
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22:34 | the dying cephalon and then everything is relative to the thalamus. Now on |
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22:39 | picture right here, what they're doing they're highlighting the green part here. |
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22:43 | there highlighting the diane cephalon. the thalamus can barely be seen in |
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22:49 | picture. All right. So you kind of see this kind of egg |
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22:52 | thing right there. What you're looking is you're looking at. So the |
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22:56 | is paired and connected. The two are connected to each other. |
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23:00 | when you do a uh mid cut through the brain, you see |
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23:06 | connector which is there and then you half of one or you see part |
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23:11 | the thalamus, the medial side of thalamus and you're missing the other |
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23:15 | So, this kind of shows you here. There was one, there's |
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23:19 | number two are left to right Alright. Now, when you're dealing |
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23:23 | the thalamus and dealing with the diet , what you're primarily dealing with is |
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23:30 | between different parts of the brain. right. That's not the only thing |
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23:34 | it does. But that's the primary . This is where most of the |
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23:40 | information comes in and then it's sent to different parts of the brain to |
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23:44 | processed. That's why we can think it. Now, we're going that |
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23:49 | are parts and also control visceral In other words, autonomic activities. |
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23:54 | that you don't have voluntary control over regulation of its things that are happening |
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24:01 | that you can experience. But you no control of. There's a lot |
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24:05 | big ugly words there. All So, what we're gonna do is |
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24:08 | gonna start with the thalamus. It's the largest part. It's the |
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24:12 | that kind of plays. And the I like to use here is the |
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24:15 | office of the brain. All So, what that means is that |
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24:20 | comes in alright, it figures out that information needs to go and sends |
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24:25 | to the proper place. Now you've heard at some point in your life |
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24:32 | humans are like the pinnacle of We are the king and queen. |
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24:40 | looking at me like no, of animals. You heard it? |
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24:44 | Well, yeah, it is. not correct basically what it is. |
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24:48 | that mammals in general are more well than, say reptiles, which are |
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24:56 | developed than say, oh, I know, fish, I'm just going |
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25:00 | use some real simple ones. now the mammals primates are more developed |
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25:07 | terms of what their brains look like say cats and dogs. All |
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25:13 | It doesn't mean that we're, you , higher orders. Just there's some |
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25:18 | issues that allow us to function the that we do. Now. The |
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25:22 | I bring that up is because if look at the cerebral um the cerebral |
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25:26 | is the structure where we kind of of high order thinking, All |
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25:31 | In other words, a big mushroom is basically this is where all the |
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25:35 | stuff happens. And then if you looking at these parts of the |
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25:38 | like the cerebellum and you look at dining Stefan, the brain stem, |
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25:43 | like, oh, those are the structures. That's what lizards have, |
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25:47 | have simple brains. They only have brain stem and there's some dying cephalon |
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25:53 | maybe some cerebellum and maybe a little of cerebral, but they're like lizard |
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25:59 | . Okay. Why do I bring this up? Well, because if |
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26:02 | look at the thalamus, you can that. It actually has its own |
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26:07 | awareness. All right. You hear philosophy. Yeah, couple of |
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26:13 | You know who Renee day cart was hear it over here. Yeah, |
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26:19 | was a drunken fart. I think I am. Yeah. So he |
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26:23 | up with the thing. I think I am alright. You probably heard |
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26:28 | at least once in your life. think therefore I am very, very |
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26:32 | . I am aware of who I . Therefore I exist is what he's |
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26:36 | saying. Well, that's what your does. It's like I am cognizant |
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26:41 | aware of my surroundings and what's going . I therefore exist. The thalamus |
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26:49 | Yeah, there's stuff around me that's crude awareness, right? There's there's |
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26:55 | , it's hot, it's cold, dark, it's light. So that's |
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26:59 | awareness when we talk about that. is icky or this is good. |
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27:04 | sort of thing. Now there are . I remember that term nuclear. |
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27:09 | it means in the brain means not inside of a cell. It means |
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27:13 | bunch of cell bodies in a network usually located in the same place that |
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27:19 | processing information and there's some nuclei that need to become aware of. All |
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27:24 | . So the first one is the Hewlett nucleus. All right. You |
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27:28 | see there's a lateral one and eventual as well. All right. The |
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27:33 | plays a role in process or sending first receives an and since auditory sensory |
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27:42 | . All right. So, you think medial auditory media is sound lateral |
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27:49 | primarily with information coming from the All right. And finally the ventral |
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27:56 | as all the other ones. All . So it kind of tells you |
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28:00 | I've got one nucleus that is geared hearing and one nucleus, it's geared |
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28:05 | seeing and sending that information on. are probably two things that we consider |
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28:13 | , very important or valuable information. . And everything else is lumped |
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28:17 | Is the other. All right. , there's other nuclei in here that |
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28:21 | not going to really spend a lot time. I don't really want to |
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28:25 | dwell too much, but basically motor . So, say it once |
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28:30 | This is why we just kind of it over on the side. There's |
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28:33 | . So the thalamus plays a role that um And basically balances where information |
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28:38 | to go. There's also some other that play a role in emotions. |
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28:43 | right. And so the two simple here fear rage are some very basic |
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28:49 | that are going to be governed within thalamus. And we're going to come |
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28:53 | to emotion a little bit later in class. The sub thalamus is just |
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28:59 | region just interior to the thalamus. , so there's some nuclear in |
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29:05 | So uh basically uh some substantial nigra some red nuclei are going to be |
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29:11 | in those two different regions. Remember were talking about those in the |
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29:16 | So they kind of just kind of up into the sub thalamus. What |
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29:20 | they do they help in terms of function? The epa thalamus is sitting |
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29:27 | here on the side. So this be the sub thalamus. They |
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29:30 | There's two structures in here. The news alert nuclei which I want you |
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29:33 | be aware of the pineal gland I you to be aware of have an |
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29:37 | nuclei plays a role in emotion, . It's involved in your visceral emotional |
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|
29:42 | to odors. All right. So you smell something like, oh I |
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29:46 | know, barbecue makes you happy. right, okay, that's a happy |
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29:51 | year old nuclear going, oh I remember this smell, it makes |
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29:54 | happy and you're like, yeah, All right. The penny a gland |
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29:58 | a role in internal timing. All . You can think of it as |
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30:02 | region where your biological clock is ticking right. And there's at different |
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30:08 | In other words, the timing of is found within structures of the having |
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30:13 | sorry, the pineal gland, the we're most familiar with is your circadian |
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30:18 | . All right. That's your sleep cycle, but it's also your |
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30:23 | You know when things are supposed to in your body also are regulated through |
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30:28 | pineal gland. The molecule that is commonly associated with that is melatonin, |
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30:34 | plays the role in the circadian You can also buy melatonin in a |
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|
30:39 | now. So yeah, the hypothalamus the sub sub thalamus. Alright, |
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30:49 | it sits below right down here. , now, what the hypothalamus is |
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30:54 | this picture doesn't do is basically a of nuclear that are responsible for regulating |
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30:59 | sorts of things in your body. . To structures of interest that are |
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31:05 | or anatomical is the mammal. Everybody's can kind of see them like here |
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31:09 | on the surface they look like a of breasts. I mean there's no |
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31:12 | way to describe it. Which is they're named the way they're named. |
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31:15 | . They're small bulges and basically they a role in olfactory reflexes and emotional |
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31:21 | to odors. So you can see that attachment there with the avenue and |
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31:26 | . Um It also has the infant which is this little structure right |
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31:29 | So there's that's the mammal everybody this here. That little little thing literally |
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31:35 | stock, like a mushroom stock. if you look at this this little |
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31:39 | that sits down, that's the pineal , sorry, not the pineal gland |
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31:42 | glands in the back, it's the gland. And so if you look |
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31:46 | the pituitary gland and it looks like upside down mushroom and that's what this |
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31:51 | is. So um so the infant is part of the hypothalamus. The |
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31:57 | gland is a separate structure now in of what it does. So here |
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32:01 | can see again, do not memorize names of all these little jelly beans |
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32:05 | here. Those are just kind of where different nuclear are located. And |
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32:09 | not interested in you understanding all the nuclear a little bit later will probably |
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32:13 | in and point out two of Um Actually it's going to be an |
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32:17 | . & p. two. So don't even have to worry about |
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32:20 | All right, you don't have to about it anytime in the near |
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32:23 | All right, so this is an control center, meaning things. You |
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32:28 | not have voluntary control over it just controls these things internally. So plays |
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32:35 | role in emotion. You can all a sudden see there's a whole bunch |
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32:39 | structures involved in emotion, just like regard to movement, body temperature, |
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32:48 | , thirst, water, balance, , wake cycle. So it also |
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32:53 | alongside with the Peniel gland plays a in controlling much of your endocrine response |
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32:59 | the endocrine system. So basically it a role in regulating hormones. So |
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33:04 | there's something that's autonomic, it's probably regulated through the hypothalamus and this is |
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33:11 | a complete list by any means. . If you have an enlarged think |
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33:16 | just greater than like bigger. typically speaking, the question is if |
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33:22 | have a bigger hypothalamus doesn't mean you a bigger response. So typically |
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33:26 | when bigger structures usually mean that something being as working extra harder. More |
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33:32 | than others. Does that always mean true? Not necessarily. But generally |
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|
33:37 | . Yes. Okay. So, don't know. I've not heard of |
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33:40 | , did someone tell you at one you have a massive hypothalamus? If |
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33:44 | did, they might be you flirting with you. I don't |
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33:49 | Nice hypothalamus. She got there. don't know. It's still funny. |
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33:58 | right. So, that gets us of the dying cephalon. So, |
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34:02 | can see their structures that are sending around and that regulate things throughout the |
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34:07 | . The last thing here is the that's this big giant structure. The |
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34:11 | when we think about a brain, what we think about. All |
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34:14 | So, it plays a role in of your consciousness. So, your |
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34:18 | , sensory perception and memory. It has a role in your intellectual |
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34:23 | So, that means reasoning, You know, your actual intelligence, |
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34:29 | motor activities, your visual activities in auditory activities. All right. That's |
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34:35 | even a complete list. It's it's just trying to give you that |
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|
34:38 | picture. My brain. My cerebral a lot. We talked about the |
|
|
34:44 | matter in the white matter previously. just reiterating this. All right. |
|
|
34:48 | , we have gray matter that's found the surface. That gray matter on |
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|
34:51 | surface is referred to as the cerebral . We have two hemispheres, you |
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|
34:56 | see the left and the right It's divided by this figure. All |
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|
35:01 | . It is functionally and anatomically meaning that different parts of the brain |
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35:07 | generally focused on doing specific functions. doesn't mean however, that just one |
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35:15 | is doing something. So, when point to something here in a little |
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35:17 | that says this is motor. Don't sit there and go, okay, |
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35:20 | , yeah, that's the only place does motor function. Okay, When |
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35:24 | say this is the visual, that's the only places doing visual cortex, |
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35:28 | you can look at these areas and can see that they're heavily geared towards |
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35:34 | in this particular area. Now, pointing this out is because if you |
|
|
35:38 | at the serial cortex here, there's six layers. The cartoon doesn't show |
|
|
35:42 | . But uh if you're in the , you may actually may actually kind |
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|
35:46 | show you and you do a cut a brain and actually you'll be able |
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35:49 | see the six layers and then depending where you're located with six layers are |
|
|
35:55 | different and structurally different. In other , the thicker the layer, the |
|
|
35:59 | neurons you find in those areas and do specific specific type of process. |
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|
36:04 | right. We don't have to worry that. I'm just pointing out that |
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|
36:08 | for future knowledge. All right, here's the longitudinal fissure, basically there |
|
|
36:14 | have let me go back to You can see that we're also |
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|
36:18 | There's a structure in here car called corpus callosum that connects the left and |
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|
36:22 | right brain to itself or to each . All right. Now, the |
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|
36:27 | hemispheres, if you look at they're not twins, they look different |
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|
36:31 | one another. All right. They're different. Typically, what we say |
|
|
36:35 | that each hemisphere is primarily concerned with opposite side of your body. So |
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36:39 | make my right hand lift up, process that over here on the left |
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36:45 | side. Okay. Typically is how think about it. All right. |
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36:49 | as I said, there is no area on any part of the brain |
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36:54 | works by itself, everything is gonna working with something else. Now, |
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36:59 | we can do though is we can the brain and say, okay, |
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37:01 | area plays a role in my This area over here plays a role |
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37:05 | sensory, this area is responsible for information. And so we have terms |
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37:10 | that. We have motor area since is an association areas and what we're |
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37:14 | to see is that we can highlight identify very specific areas for some very |
|
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37:20 | functions. All right. Even though are kind of like nebulous areas. |
|
|
37:24 | right. So what I want to is focus on the motor areas |
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|
37:28 | I want you to look at this on the left and I want you |
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|
37:30 | tell me do you notice something about motor areas in the picture? Mm |
|
|
37:38 | . Okay, everywhere. Let's Here's the parietal lobe. Is there |
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|
37:42 | in the problem? How about the ? That's all in the front |
|
|
37:49 | Oh, yeah. Well, the are pretty. Yeah, that's |
|
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37:53 | They can be confusing to, you , I was like, oh, |
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|
37:57 | pretty colored. Yeah, but all . What I want you to focus |
|
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38:01 | here is that motor areas are in frontal lobe? Okay. So when |
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38:06 | think about movement, movement processing begins the frontal lobe. All right. |
|
|
38:13 | have a couple of areas I want point out. All right. We |
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|
38:16 | the primary motor cortex or the primary cortex is located here in the pre |
|
|
38:23 | gyrus. All right, Broca's For those of us who speak |
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|
38:29 | What's the word for mouth boca. . We have Broca's area named after |
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|
38:36 | person who discovered it, Broca's area responsible for speech production. All |
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|
38:44 | So, for those you took your , if you're in texas and you |
|
|
38:48 | your first language choice, you go spanish. You don't go with french |
|
|
38:51 | my daughter did because she's never gonna a word of french ever. Everybody |
|
|
38:58 | want to take french. That's a german language. Yeah, I'm just |
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|
39:03 | I'm going swinging for that one. . I mean, come on water |
|
|
39:09 | every language makes sense. Except for french. Oh yes. What? |
|
|
39:16 | , E A U O Not even with an O. Mhm. And |
|
|
39:26 | is how we learn stuff. Actually, if you didn't know the |
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|
39:31 | and german is there, they're from same tribe. French is a Germanic |
|
|
39:37 | . That's why I say it's a form of german. English is a |
|
|
39:40 | form of german with some other things into it. Well, actually, |
|
|
39:45 | like jumble is just whatever than the . We're just going to throw it |
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39:48 | there. All right. Broke his controlling speech the muscles that make speech |
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39:56 | . All right. And then we the frontal eye field. This is |
|
|
39:59 | superior. So here's Broca's area in frontal eye field is just north of |
|
|
40:04 | . Or superior to that. It controls voluntary eye movement. Everyone without |
|
|
40:08 | your head. Look up, look , look up again. Look to |
|
|
40:12 | left. Don't trust that person. to the right, that one. |
|
|
40:15 | don't know. He's kind of sketchy . All right, that's the frontal |
|
|
40:21 | field is being able to move your around like that. So, do |
|
|
40:24 | notice that movement, isn't it? , My mouth making these noises that |
|
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40:29 | can understand is movement. All okay. The understanding parts a little |
|
|
40:35 | later. We're gonna talk about where area as well. All right. |
|
|
40:39 | this is the primary motor cortex, can see here. It maps out |
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|
40:43 | very specific parts of the body. is what is referred to as a |
|
|
40:47 | . So it's what we say is to typically or summat open. I'm |
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|
40:53 | going to say when I started thinking some data, topically organized as the |
|
|
40:57 | I'm looking for. All right. so you can see does this look |
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|
41:00 | a human? No, but does have all the parts of the |
|
|
41:05 | Yeah, just kind of all weird arranged weird. Which is why we |
|
|
41:08 | to it as a homunculus. And you can see, look, it |
|
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41:12 | the body just fine. And then have these regions that are thick or |
|
|
41:16 | and that's kind of weird. It's why would I have a weird big |
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|
41:20 | hand versus say not a big giant . All right. How many |
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|
41:28 | Play piano gone? All right. two people raised three people. |
|
|
41:33 | 4, 55 out of 400 I know that's a lot. The |
|
|
41:37 | of you just aren't playing my I'm looking at the three of you |
|
|
41:40 | . You guys like I do, not going to raise my hand. |
|
|
41:44 | . Yeah. Yeah. Okay. he's hiding behind his mask. All |
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|
41:49 | . Does it take a lot of to do this and putting them in |
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|
41:54 | right place on a keyboard. it does. Right. We have |
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42:00 | motor movement in our hands. I all right, fine, no pm |
|
|
42:04 | many guys know how to write? we go. Alright, so the |
|
|
42:09 | of your pin on that paper is result of fine motor movement. That's |
|
|
42:13 | our hands have these math is massively on our brains. All right. |
|
|
42:20 | basically saying a lot of your brain dedicated to the movement of your |
|
|
42:25 | All right, look at your Why do you think your face is |
|
|
42:28 | big? I think that sounds just funny. Why is your face so |
|
|
42:33 | ? Uh huh. Yeah. Did know the majority of our communication is |
|
|
42:38 | through facial expression, yep. And all wearing your masks are now basically |
|
|
42:45 | learning how to communicate. You guys old enough that you know how to |
|
|
42:48 | like the young kids, they're not failing to learn how to communicate because |
|
|
42:53 | wearing masks. All right. But what it is. When you see |
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|
42:57 | do this when I come into the . I mean, I'm tired. |
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|
43:03 | usually the answer yet. It's usually , right? Someone's pissed me off |
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|
43:08 | you don't want to mess with right? If I come in, |
|
|
43:12 | insane. Right? So that's that's be again, that's all represented by |
|
|
43:19 | muscles of the face again, Why is our tongue big? Keep |
|
|
43:23 | to yourselves? Yeah, Yes, actually communication again. Right? And |
|
|
43:30 | pharynx as well. All right, , when you see a map like |
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|
43:36 | , Understand that it has it's not a map of like Google Maps. |
|
|
43:41 | know, it's not specific. It's like a map from the 1400s, |
|
|
43:46 | ? You've seen the map from the and he's like, he's like, |
|
|
43:48 | this is a kind of a We think it kind of looks like |
|
|
43:51 | . And over here there's a mermaid ? Over here is a dragon. |
|
|
43:55 | not we're not 100% certain we think dragons over here. All right. |
|
|
44:00 | kind of what this is. Is it just it gives a general idea |
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|
44:04 | when we mapped this out, this kind of vague area. And so |
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|
44:09 | like, well if I well let's for example, if I lose my |
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|
44:13 | , right, I've lost my hand I played with the wood chipper. |
|
|
44:18 | ? Look, I need to go that. I've lost my hand. |
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44:21 | my brain going to still want to a lot of time trying to process |
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44:25 | to move my hand. No. so what's going to happen is that |
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|
44:29 | is going to shrink as other parts my body are then um Magnified is |
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|
44:35 | the word I'm looking for is adapting you. That's probably the best |
|
|
44:39 | right, is adapting to my new of stump penis. All right. |
|
|
44:46 | what we say is that it can plasticity. So it's not an accurate |
|
|
44:50 | . It's a representation of the regions the brains and where that information is |
|
|
44:55 | processed. All right. So that that was the motor homunculus. And |
|
|
45:00 | I told you bro, cause I the frontal eye field as well. |
|
|
45:05 | , notice. Now here's that map where the sensor area is located everywhere |
|
|
45:12 | , but the frontal lobe, thank . All the pretty colors. All |
|
|
45:17 | . Now, I'm pointing out, at the words I'm using here. |
|
|
45:21 | , primary, primary, primary If there's a primary, that must |
|
|
45:25 | there must be a secondary. And so what we're doing is in |
|
|
45:29 | map we're trying to show you where primarily located and where the primary cortex |
|
|
45:35 | the processing takes place for these different . All right. So the somatosensory |
|
|
45:41 | is located here in the parietal in the post central gyrus. |
|
|
45:46 | so that central sulcus divides the pre in the post central from each |
|
|
45:52 | So, we got motor on the we have sensory on the pope. |
|
|
45:56 | at that in just a moment. , so that's the Madison to me |
|
|
45:59 | touch. Primary visual cortex back here the occipital lobe. All right. |
|
|
46:04 | visual input from the eye. The auditory cortex is located here in the |
|
|
46:10 | lobe. That's for the hearing. have the olfactory cortex. This is |
|
|
46:14 | located on the temporal lobe. But you have to do is you have |
|
|
46:17 | kind of open it up and look the other side. So that's the |
|
|
46:20 | of smell and then finally down here the insula that's where the primary gustatory |
|
|
46:26 | is located. That's a sense of . In the next unit. We're |
|
|
46:29 | to talk about each of these special . So, here's the primary somatosensory |
|
|
46:36 | . Homunculus. Again, you'll notice there's a shape. Look at the |
|
|
46:41 | , look at the face, look particular the lips. Why do you |
|
|
46:45 | the lips are so big on the ? What's that? Maybe? How |
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46:52 | ? Okay, But it's even in , it's big for kissing, isn't |
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47:00 | ? No, No. You're not go that direction. Yeah. |
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47:03 | she alright. She likes to Good. Good. All right. |
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47:08 | not going to make the jokes there sorry, I'm not I'm not but |
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47:14 | a reason we like to kiss. right. It's because it's sensitive. |
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47:18 | right. But I want you to for a moment about food, mm |
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47:24 | . All right. What is the way for horrible things to get in |
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47:30 | body through the mouth? All Have you ever eaten something that's too |
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47:35 | for you? Starbucks? Coffee. . Burn your lips. Burn your |
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47:41 | right. Right. If something is like it's gonna stab you a |
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47:47 | Yeah. All right. Something's Yeah. All right. Just |
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47:57 | there's there's sea. That's right. levels of know that are just like |
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48:01 | , but you know, you're sitting eating a bowl of Doritos and I |
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48:05 | know, cockroach crawls into that. , you're not looking. I |
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48:10 | I'm sorry. It's gross, but could happen. The world is a |
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48:15 | place. Cockroaches crawl places, you . All right. Your lips are |
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48:24 | to let you know what you're putting your mouth. Okay. It's a |
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48:30 | because you don't have the protection on inside that you have on the |
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48:34 | All right. Your tissues inside your are soft and damage a ble right |
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48:40 | the outside. I can pour coffee my on my body out here and |
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48:44 | sucks, but I'm not going to , Right? But 360° coffee on |
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48:49 | inside of my body is going to all sorts of damage. And that |
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48:53 | temperature. Starbucks shoots 360°. 1 Yeah, I'm just like, |
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48:59 | it's like super, super hot. like lava. It's like they get |
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49:03 | and they put in a couple and say, drink this and it's |
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49:06 | okay, it doesn't have caffeine. like, yeah, So, that's |
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49:09 | you're drinking the lava. All Now, notice again, has specific |
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49:15 | . It follows the body plan, like the muscles do. All |
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49:19 | And again, just as before it uh, has plasticity as well. |
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49:26 | right. Now, notice I didn't a lot of time talking about the |
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49:33 | ones. Did I? Because we to talk about in the next |
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49:36 | All right. So, I just to deal with the S1 status sensory |
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49:41 | association areas association area. Remember as said is responsible for processing information. |
|
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49:48 | . It integrates information from different All right. And so we have |
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49:54 | of them notice they're found all over brain. So, for example with |
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49:57 | pre motor cortex. All right. is located in the pre uh just |
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50:03 | to the pre central gyrus. if this is where I'm gonna send |
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50:07 | down to the muscles, maybe when come up with a plan, I |
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50:11 | be able to send that to the the nerves or the area that processes |
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50:15 | it sends off. And that's really the pre central or three motor cortex |
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50:19 | . It basically plays a role in movement. It plays a role in |
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50:24 | how to do uh repetitive or pattern . See, I'm already dipping my |
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50:30 | into these dangerous zones of Here's another that plays a role in motor movement |
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50:35 | in terms of movement. All Once you start seeing it's like, |
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50:40 | , there's a lot of places, playlist job and movement. All |
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50:43 | We have the Samantha sensory association basically allows you to process information about things |
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50:49 | you touch. All right, you your hand into a dark thing and |
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50:55 | feel something warm and fuzzy rabbit better a rat. That's what I was |
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|
51:01 | of. Alright. Or a cat something. But if you feel for |
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51:06 | warmth, you know, then you that it's something that's living. I |
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51:10 | your brain picks up on all the I said, oh, when I |
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51:13 | this and this and this it means . All right. That's the |
|
|
51:20 | Did you, when you guys were like in like third grade or |
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51:23 | did they ever do that where they you and your hand is something you |
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51:25 | to kind of figure out what it . No, I mean it's |
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51:29 | oh, it's a tennis ball. , it's a porcupine, that sort |
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51:32 | stuff. All right. So that's the cement essentially association area does. |
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51:37 | visual association area. All right. going to be located in the occipital |
|
|
51:42 | . So it's kind of in this and time out. Don't write this |
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|
51:46 | . Visual basically goes all the way like this and then it goes all |
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51:50 | way like that. It's it's All right. But like the like |
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51:53 | immediate uh visual association is basically it information. All right now, I |
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52:01 | know how much we're going to get this for the next thing, but |
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|
52:03 | want you to think about this one you look at something, your eyes |
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52:07 | not a camera and it's not projecting movie to the visual cortex. What |
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52:12 | does is that information is broken down then each part of that information is |
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52:19 | processed independently. And then each of things are then uh reorganized in your |
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52:25 | to tell you what you're looking All right. And so I have |
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52:28 | here, for example, I have , movement and form. So color |
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52:33 | there are areas of brains, the name ever. They're called blobs. |
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|
52:39 | . Yeah. Yeah. And the I called blobs because they're nebulous |
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52:44 | And once you start diving into the organization around visual stuff, that's when |
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52:49 | want to just throw it and just , no, I am going to |
|
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52:52 | school. All right. It's just complicated. I mean, I find |
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52:57 | think it's complicated. I'm telling you complicated. All right. I'm looking |
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53:00 | it. And like, I don't it. All right. And then |
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|
53:03 | you're neurologists are like, what we something you don't know. All |
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|
53:09 | But in essence still color. It's from movement. And it's really |
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|
53:14 | The experiments they did from movement. took cats. I shouldn't tell you |
|
|
53:18 | , but basically, they basically cut portions of the brain up. You |
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|
53:23 | , like, damage it. And what they did is they process so |
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53:26 | they could only detect movement in one or in a different direction. And |
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|
53:30 | really, really interesting. This was in the 50s. So it wasn't |
|
|
53:33 | yesterday Fauci wasn't doing it. See, did you see the timing |
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53:38 | that joke? That was that was time to joke. Okay. |
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|
53:43 | And there's also form form is right? So, you know when |
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53:47 | see a shape you're like that is blank right. You see a shape |
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53:50 | a tree. That's a tree, , you know that's a bush and |
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53:53 | can have that argument because form has stuff. So that's what we're talking |
|
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53:58 | . So all that information is processed and then it's checked against memory and |
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|
54:03 | how you are able to identify things . Lastly, is auditory cortex and |
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54:09 | temporal lobe. There's an auditory auditory here in the temporal lobe basically it |
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|
54:15 | you to integrate sound and allows you recognize sound, right? So when |
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54:19 | hear whack, whack, whack, know that's doctor wine making a duck |
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54:26 | . Okay. All right, So I said we have 2/2 |
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54:35 | Each have basically uh are not exactly same, but they're very similar to |
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54:40 | other. So there is a division labor. There have very functional |
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|
54:46 | Now, having said that, I you to understand that doesn't mean that |
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54:51 | handedness and left handedness or right brain left brain exists. I mean you've |
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|
54:56 | people say that while I'm right I can't learn this because I'm right |
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|
55:00 | , that's a lie. Alright, it says is that the processing of |
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55:04 | things occurs on different sides doesn't mean you're better at something or less capable |
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55:11 | something just because of that sightedness. . So there's no preferential use of |
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55:17 | left of the right brain. What usually is lateralization correlates highly with handedness |
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|
55:24 | so typically what we say, most us are right handed basically. It's |
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55:28 | oh well that means on the left side, that's where we're primarily processing |
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55:34 | for movement and not really. But is a correlation for it. All |
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55:40 | left hemisphere is typically speech dominant, most people Yeah, handedness as |
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55:47 | you know, physical ability. And it already shows you most of us |
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55:51 | right handed but speech is also on left side. All right. And |
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|
55:57 | Broca's area is broken is primarily located the left hand side. All |
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56:02 | And so that's going to be true both right handed and left handed |
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|
56:08 | All right. So the point in that was in terms of lateralization, |
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56:12 | brain divides up and again, you need to memorize the colors and what's |
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56:17 | in each of them right? But it basically says that the brain Debbie's |
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56:21 | work. He says left side, do this right side, you do |
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56:25 | and it doesn't matter if you're left or right handed to do that. |
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56:30 | more or less the same. getting down to the last little |
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56:38 | I think we're gonna get out early . Uh huh. Maybe I should |
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56:44 | down. Nice. I do. . Are you sure you want me |
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56:51 | go fast? So I get done three slides, don't you? |
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56:55 | you have six slides. I have 30 minutes, right? Or like |
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57:02 | minutes. They're going to go by because basil nuclearize fast. All |
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57:07 | basil nuclear ice, you'll hear. people refer to as the Babel basil |
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57:11 | . This is gray matter centrally located the brain. In other words, |
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57:15 | gray matter just isn't on the Remember? It's like an oreo. |
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57:19 | have gray and white and gray. , we're focusing on that internal |
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57:24 | All right. So, it's located a whole bunch of different areas and |
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57:28 | job once again plays a role in . See, I told you not |
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57:34 | this. All right now, primarily it does. It plays a role |
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57:40 | inhibiting antagonistic movement. All right. doesn't have direct access to the motor |
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57:46 | . Just like the cerebellum, cerebellum talk to the muscles. The thalamus |
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57:50 | talk to the muscles. The pre cortex can't talk to the muscles. |
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57:55 | the motor cortex can talk to the . All right. So, everything |
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58:01 | basically processing information to create something Now when you think of the basil |
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|
58:08 | , the easiest way to think about is Parkinson's disease. Have you ever |
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|
58:11 | about Parkinson's disease? Alright. Parkinson's . The primary uh feature of |
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|
58:17 | There's a lot of them and he's it is the tremor okay? It's |
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|
58:21 | see them. You'll see people will doing this All right now. You |
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58:25 | do a trimmer. But you have same thing going on in your brain |
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58:30 | what's going on inside A person who Parkinson's okay. Whenever you make any |
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58:35 | of movement, you're going to make in your movement. All right. |
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58:39 | I'm reaching for the bottle, my is going towards the bottle and it's |
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58:43 | nice smooth movement. Right? But going on is I've got muscles that |
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58:48 | contracting and maybe I have a muscle contracts a little bit too much and |
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58:52 | me a little bit to the And so my brain says, |
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58:54 | no. Remember Sarah Palin says, the plan. You're failing in your |
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58:58 | . You need to make corrections in time. So it makes a correction |
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59:01 | it even happens. So the action slower than the processing and so all |
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59:07 | corrections are being made along the That's why I have a smooth movement |
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59:11 | Parkinson's what's happening is we damage regions the basil nuclear which are responsible for |
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59:18 | those corrections. All right. So said, hey, inhibiting antagonistic or |
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59:24 | movements. So when I am over , I need to make an antagonistic |
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59:29 | to go the opposite direction. All . And so what's happening is I |
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59:34 | out the movement before you ever see If the basil nuclear isn't doing |
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|
59:38 | then you're seeing that antagonism going on so that's why you start seeing a |
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59:45 | having the tremor, their muscles are to maintain a steadiness but they can't |
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59:52 | they're not processing correctly, That kind makes sense. So that's true, |
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60:00 | lot of people do have tremors but in particular its damage to the base |
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|
60:04 | nuclear from Parkinson's. Another characteristic of is watching him trying to change |
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|
60:10 | Alright, so my grandfather long before passed away, he had Parkinson's, |
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60:15 | ? So there's a guy who played up into his eighties and then Parkinson's |
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60:18 | and so it was kind of you know, it's always sad, |
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|
60:21 | know, but you'd see him make and so he'd be moving in a |
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60:26 | and he'd want to shift and so he'd do is he'd slow himself down |
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60:30 | then he'd have to do this before starts moving again. Then you can |
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|
60:34 | up speed again, right? And the idea here is again is he |
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60:39 | the brain while it's making a it can't control the muscles in the |
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60:43 | that it wants to and so it's the plan is getting mucked up |
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|
60:47 | it's like you do whatever you want her crew done. Uh so Parkinson's |
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|
60:54 | still trying to figure out why. , it's like alzheimer's, it's |
|
|
60:58 | well we got a bunch of theories every time we think we have |
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|
61:01 | we don't right, we'll figure it . Trust me by the time you |
|
|
61:06 | are you going to live to black which will be really sad because we |
|
|
61:10 | know how to do youth yet, we can figure out youth first how |
|
|
61:15 | maintain youth forever than living forever is , I guess. I don't |
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|
61:22 | All right, so let's walk through structures scary names, why are we |
|
|
61:32 | ? Oh sorry, it's hard, hard to give up a bad |
|
|
61:38 | All right. She asked me why you still doing that? Are you |
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|
61:42 | us because it's fun up. All , first is corpus um excuse |
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|
61:51 | Something for a couple of different So these structures under here are all |
|
|
61:58 | of the corpus striatum. All so you can see here here's the |
|
|
62:02 | , this part right? Here is link to form nuclei. There's two |
|
|
62:06 | to it. We have the global and we have the classroom. |
|
|
62:10 | I said the human and the global . Alright, still the caudate nucleus |
|
|
62:16 | up here, basically the rhythm of arms and the legs. Right? |
|
|
62:23 | was really weird looking. It should the opposite. Well, no, |
|
|
62:27 | looking. Yeah, so it should this. Alright, that's more |
|
|
62:33 | Alright. Central pattern generator. Peterman movement at the subconscious level. Have |
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|
62:41 | moved around without thinking about it? you go. Right, globus played |
|
|
62:47 | , that's going to be doing the adjustment to the muscle tone. So |
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|
62:51 | is one of the areas that gets affected by Parkinson's down here, we're |
|
|
62:57 | see the mongoloid body again, but the mongoloid body is part of the |
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|
63:01 | nuclei. It plays a role in , behavioral activities and development of your |
|
|
63:05 | . And particularly mongoloid body is going play a role in fear when we |
|
|
63:10 | to it. And lastly we have little tiny structure right here in the |
|
|
63:14 | . All right. It's not you're at a slice so it looks like |
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|
63:17 | really thin thing, but it's actually a band that goes around the whole |
|
|
63:23 | of your cerebral like this. So basically comes all the way around and |
|
|
63:28 | players are a job of processing visual and again, at the subconscious |
|
|
63:34 | it's not stuff that you think It's just processing visual input. All |
|
|
63:38 | . So there are structures that I you to be most familiar with and |
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|
63:42 | a very generic way. What's cost processing? What does the global |
|
|
63:47 | This duo, basically it affects how thalamus adjusted uh muscle contraction. What |
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|
63:53 | a peterman do? Basically processes Alright. We don't have to think |
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|
63:57 | it. That's what I'm looking for . I'm probably not going to give |
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64:01 | a picture. I'm almost certain. don't give you a picture like this |
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|
64:04 | say label it. Yes, limbic . I have a better one that |
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|
64:13 | like a space shrimp. Right, got rid of that one for this |
|
|
64:18 | olympic system. Easy, so It's emotion. All right. How |
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|
64:24 | you feel right now? Happy or happy olympic system. How do you |
|
|
64:28 | right now? It's tired. Yeah, yeah. Motion All |
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|
64:37 | It does play a role in It plays a role in reproduction. |
|
|
64:42 | plays a role primarily an emotion which why we bring it up mood and |
|
|
64:46 | nutrition. Alright. And really why has all these things is because it's |
|
|
64:51 | located in all these different structures are putting out putting from there. All |
|
|
64:57 | , So, basically you can imagine is your dying Stefan. It's been |
|
|
65:01 | or less removed so that you can the structures of the limbic system. |
|
|
65:05 | so thank you. This is why doing all these different things. All |
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|
65:10 | . So, I'm just pointing this because you'll see it always named the |
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|
65:15 | gyrus. Alright, The singular gyrus part of the cerebral when you hear |
|
|
65:19 | thinks cerebral. Alright, so it part of the cerebral and it plays |
|
|
65:26 | role to help process memory. All , it does. So with the |
|
|
65:32 | and the para hippocampal gyrus again, you hear the word gyros part of |
|
|
65:37 | cerebral. Alright, now, hippocampus a structure that goes around like so |
|
|
65:44 | named the hippocampus because it looks like hook print. Alright. Para hippocampal |
|
|
65:49 | , basically it goes alongside the So it's next to the hippocampus. |
|
|
65:56 | , what it does memory, which gonna learn about him? Just second |
|
|
66:00 | ? Actually we don't So special ladies, you're really, really good |
|
|
66:04 | this. Guys were terrible at I want you to get ready, |
|
|
66:09 | , because in your future there's gonna a guy that says I can't find |
|
|
66:13 | . You're gonna roll your eyes. remember I said this and you can |
|
|
66:17 | it's real simple. It's right here we put this? This is an |
|
|
66:22 | battle between me and my wife with in our house. In fact, |
|
|
66:27 | don't look for stuff now. I asked her to go find it for |
|
|
66:29 | because she knows where it is. right. I mean, Guys, |
|
|
66:34 | know what I'm talking about right It takes me 40 minutes to find |
|
|
66:36 | peanut butter. Yeah. Alright. can't find the peanut butter. I |
|
|
66:40 | it right here. It's no longer . Have you looked on the shelf |
|
|
66:44 | ? Yes, walks up peanut Where to go, spatial memory. |
|
|
66:57 | right, navigation. Ladies, men really good at navigation. There's actually |
|
|
67:07 | , actually it's there's been many, studies. Alright. Again, the |
|
|
67:12 | between the biological sexes are actually expressed some of these activities. All |
|
|
67:20 | I'm not saying men are are excellent will be stubborn as all get |
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|
67:25 | If we think we know where we're . We will be, nope. |
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|
67:28 | I guarantee yesterday, my wife, are we going this way? Because |
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|
67:33 | avoiding the traffic here here and here get to where we need to |
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|
67:37 | Which is I could have gone the that she chose? But I chose |
|
|
67:39 | get there today instead of like three from now? Uh huh. All |
|
|
67:44 | . She can't my wife can't process I can't visualize the path until I'm |
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|
67:50 | it. Me. You could blindfold to spend around 30 times and I |
|
|
67:56 | tell you where I am which direction facing and how to get there from |
|
|
67:59 | to b. If I've ever been once I can get there any |
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|
68:04 | It's crazy. Yeah, none of is everybody. This is all |
|
|
68:10 | Let me back it up just to you guys understand curve. There's always |
|
|
68:15 | be people on the edges, But there's a general population that correlates |
|
|
68:20 | the idea. All right. Um see verbal memory learning and computational information |
|
|
68:28 | storing memories and forming long term. is one of the last things we're |
|
|
68:31 | talk about today. All right. very briefly talk about it. All |
|
|
68:35 | . Now remember memory isn't all stored . This is where information is |
|
|
68:41 | So that a pattern is created and in the Sorry, I should be |
|
|
68:45 | at the frontal lobe. Okay. a lot of memory goes. All |
|
|
68:49 | . Made alloy body is the amygdala And this is where fear is all |
|
|
68:55 | . So again scoring emotional perception, that and also plays a role in |
|
|
69:01 | and emotional behavior. So you went basic did you have one of those |
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|
69:05 | surrogates that yelled at you get in face and yell at you. Did |
|
|
69:09 | cry? So what did the sergeant when they cried out? They |
|
|
69:14 | Really? Okay. So I figured sergeant, would you yell louder and |
|
|
69:20 | them cry more? Okay. But then people figured out he's not |
|
|
69:25 | to beat me up, He's not to eat me. So they learned |
|
|
69:27 | to keep that straight face when you that. Yeah. So it was |
|
|
69:29 | trained behavior. Right? So my here is, so when someone gets |
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|
69:35 | your face and start screaming, your response is to do what cry |
|
|
69:41 | fight right there? There's a natural that we all have, right? |
|
|
69:48 | what they're trying to do and basic trying to get you beyond the natural |
|
|
69:53 | and learn how to basically, I'm trying to be stoic, but in |
|
|
69:58 | case learned behavior so that you respond . It's a trained behavior. All |
|
|
70:03 | . But the amygdala plays a role that first that first step. Uh |
|
|
70:08 | is my natural response, right? it. No, not necessarily. |
|
|
70:14 | it's how we're fairies. So for , you go um you go in |
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|
70:18 | woods, you see a bear, response is going to be. This |
|
|
70:21 | a dangerous animal, I'm afraid. ? So next time you go in |
|
|
70:24 | woods, you're gonna be, you're go bears. Bears are in the |
|
|
70:30 | and they do horrible things. All right? But if you watch |
|
|
70:34 | movie with bears, you're probably gonna , oh they're cute and cuddly. |
|
|
70:37 | want to hug them. Don't hug bear hugging bears. Bad. All |
|
|
70:45 | . Um Olfactory bulb is part of tracks. Remember we talked about smell |
|
|
70:49 | memory? Um Actually we did a bit a little bit later. I |
|
|
70:53 | earlier, but the idea if I something, it probably can trigger a |
|
|
70:56 | , trigger an idea, trigger an . So again, the for next |
|
|
71:01 | the region I should point out the bulbs, right? There is a |
|
|
71:05 | X basically connects all these structures And then there's a whole bunch of |
|
|
71:08 | nuclear that are not being shown here play a role in connecting these different |
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71:13 | and processing information. The big picture the idea here behind the limbic system |
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71:18 | the limbic system processes emotions. Last slides the right to slides memory. |
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71:28 | right. In looking at these two I wanted to try to push here |
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71:33 | this idea of plasticity in the We've already mentioned this, right, |
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71:38 | the brain can change in response to stimuli and that we can hold onto |
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71:42 | stuff for a long period of There's things that are called long term |
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71:46 | in short term memory. But the is that I'm creating a pattern or |
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71:49 | change in the brain. All And that's what this is trying to |
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71:51 | . It's like, look here is this this interaction is between these two |
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71:56 | looks like, you know, it's nice simple action potential, Right? |
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72:01 | after repeated stimuli, what's going to is there's changes going to occur. |
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72:06 | the amount of neurotransmitter or the amount receptors on the surface are going to |
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72:12 | and you can see there's three versus madam neurotransmitter being released is supposed to |
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72:16 | a lot more, even though they show it there. And so what |
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72:19 | up happening, I get a much response between these two cells. All |
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72:24 | . And so this is kind of of the things that memory, how |
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72:27 | is formed is changing interactions between All right. So, it's first |
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72:36 | , memory is not stored as a . We've talked about this. It's |
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72:40 | a pattern of interactions between neurons in network. And we can do one |
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72:45 | two things to change those interactions. is called long term potential Haitian or |
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72:50 | term depression. Now, this is depression as in like boo hoo. |
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72:54 | sad. Alright. Depression means I'm the interaction. So, what we're |
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72:59 | at here is an example of long potential Haitian. All right. |
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73:04 | in essence what I've done is I've the interaction so that I'm getting an |
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73:08 | response between those cells. Long term on the other hand, would be |
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73:12 | I change the interaction. So I'm a diminished or reduced response between those |
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73:18 | . So I might not be getting action potential or I might not be |
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73:22 | um I'll have say even less. if I have three here maybe I |
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73:26 | one receptor instead of four of These release a neurotransmitter. I would get |
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73:33 | two is the idea. So when thinking about memory, what we're doing |
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73:37 | we're changing interaction. This is that were referring to now there's different types |
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73:43 | memory. Alright. There's sensory This is very very brief memory in |
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73:48 | words, stuff that we remember from seconds. You know like in |
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73:52 | Like okay it's bright. Right? so its associations with your environment is |
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73:58 | kind of the the idea. But you're paying attention to it you can |
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74:02 | move that into short term memory. right. The idea here is I |
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74:07 | hold on to for a little bit while and this is in the |
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74:10 | hippocampus is playing a role in And then what happens if I go |
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74:15 | repeated practice then I can turn short memory into long term memory. That |
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74:22 | practice is taking these ideas and consolidating them. It's what the process |
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74:27 | called consolidation. So the idea is we're bringing in the frontal lobe and |
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74:34 | is what we're doing is we're repeating creating this pattern for consolidation. So |
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74:39 | term memory very very very very brief other words we're talking minutes. I'll |
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74:46 | you an example. Who can tell what you had for lunch, last |
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74:51 | . Mhm. All right. if you have the same thing every |
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74:55 | , it's a pattern of behavior. , that doesn't count. Right? |
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74:59 | if you have to think about, have to kind of go back and |
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75:01 | like, okay, I can't I don't know if something special happened |
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75:04 | day you may remember. Right? what you've done is you've changed it |
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75:09 | short term to long term because of there. All right. Long term |
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75:15 | occurs as a result of practice. right. Or some something that really |
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75:20 | of makes it stick. All And so that's this this idea of |
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75:26 | rehearsal. And then so then you that pattern. You can basically hold |
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75:31 | to anything and everything limitless lee. other words, there is no limit |
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75:36 | how long you can hold it and not a limit to how much you |
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75:39 | hold. The difference is. And me be really clear here. Is |
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75:43 | once it goes in your brain isn't to stay there forever. Not unless |
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75:47 | practice it. Okay. So, I told you, I did a |
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75:51 | of work when I was a grad doing a whole bunch of stuff. |
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75:55 | if you came and asked me now the things I did, I'd stare |
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75:58 | you and go, I couldn't tell . But there's a lot of stuff |
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76:01 | I learned. I just haven't practiced . All right now, this |
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76:06 | cerebral cortex so notice we're doing this in the hippocampus that ultimately goes to |
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76:14 | terms of long term memory into the that's where we start. So, |
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76:23 | test. All right. Remember extra opens up tomorrow at six PM, |
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76:30 | thursday morning at nine and then the the second one opens up at six |
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76:35 | On thursday. I have an answer you know |
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